Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475905 | 1.00 | HTR1A (0.52) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5473410 | 0.92 | HTR1A (0.51) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5473416 | 0.92 | HTR1A (0.51) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5478896 | 0.88 | HTR1A (0.51) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5478890 | 0.88 | HTR1A (0.51) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5481090 | 0.87 | HTR1A (0.58) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5858732 | 0.79 | HTR1A (0.53) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5858360 | 0.79 | HTR1A (0.53) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5858801 | 0.79 | HTR1A (0.53) | HTR1AHTR1DHTR2BADRA1ADRD2 | |
| SCHEMBL5858707 | 0.79 | HTR1A (0.53) | HTR1AHTR1DHTR2BADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | claimed |
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | HTR5A, HTR1A, HTR2C | HTR1A 2/4885HTR1D 6/4885HTR2B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.