SCHEMBL547607

SCHEMBL547607

O=Cc1ccccc1C1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
TSHR P16473 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
PTGS2 P35354 1/20 0.39
SRC P12931 1/20 0.37
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CEL P19835 2/20 0.35
GAA P10253 1/20 0.34
PTPN1 P18031 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31415807 1.00 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL14237042 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL21647623 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL22284134 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL197356 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL11675315 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL14236917 0.98 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL548161 0.98 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL548147 0.91 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL6764461 0.82 MEN1 (0.43) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
US-9620363-B2 Underlayer film-forming composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN disclosed
CN-118027260-A High-selectivity polymer material with adjustable repeating unit carbon skeleton structure and preparation method thereof 大连理工大学 2024-05-14 CN disclosed
CN-116282078-A Salt recovery solution and method of using the same 阿克福特斯技术有限公司 2023-06-23 CN disclosed
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
CN-111225875-B Salt recovery solution and method of using salt recovery solution 阿克福特斯技术有限公司 2023-04-11 CN disclosed
CN-115449262-A Marking composition 桑福德有限合伙人公司 2022-12-09 CN disclosed
CN-108369892-B Method for treating object, composition for temporary fixation, semiconductor device, and method for manufacturing semiconductor device JSR株式会社 2022-07-05 CN disclosed
CN-111263795-B Reversible thermal discoloration aqueous ink composition and writing instrument using the same 株式会社百乐 2022-05-03 CN disclosed
EP-0468974-A4 NOVEL HMG-COA REDUCTASE INHIBITORS 1992-03-25 EP disclosed
EP-0468974-A1 NOVEL HMG-CoA REDUCTASE INHIBITORS RORER INTERNATIONAL (HOLDINGS), INC. (US) 1992-02-05 EP disclosed
US-5001128-A HMG-COA reductase inhibitors RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-03-19 US disclosed
WO-1990010444-A1 NOVEL HMG-CoA REDUCTASE INHIBITORS RORER INTERNATIONAL (HOLDINGS), INC. (US) 1990-09-20 WO disclosed
US-4904691-A Novel HMG-CoA reductase inhibitors RORER PHARMACEUTICAL CORPORATION (US) 1990-02-27 US disclosed
US-4407823-A ANTIINFLAMMATORY AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1983-10-04 US disclosed
US-4377689-A Process for preparing spiro derivatives ETABLISSEMENTS NATIVELLE S.A. (FR) 1983-03-22 US disclosed
US-4371538-A Spiro derivatives, process for their preparation and medications containing same ETABLISSEMENTS NATIVELLE S.A. (FR) 1983-02-01 US disclosed
US-4254035-A BY REACTING GLYCINE AND AN AROMATIC ALDEHYDE IN THE PRESENCE OF ACETIC ANHYDRIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-03 US disclosed