SCHEMBL547626

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL548166	0.82	CYP1A2 (0.54)	ALDH1A1TSHRHTTNPSR1MAPT
	SCHEMBL20563883	0.75	ALDH1A1 (0.48)	ALDH1A1SMN1; SMN2TSHRLMNAHTT
	SCHEMBL71815	0.73	CYP2C9 (0.61)	ALDH1A1SMN1; SMN2TSHRLMNAHTT
	SCHEMBL339284	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT
	SCHEMBL31097913	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT
	SCHEMBL2481923	0.73	TSHR (0.50)	ALDH1A1SMN1; SMN2TSHRLMNAHPGD
	SCHEMBL11529757	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT
	SCHEMBL2696567	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT
	SCHEMBL2207056	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT
	SCHEMBL29229419	0.73	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.