SCHEMBL547663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL547627	0.86	MAPT (0.44)	MAPTCYP3A4KDM4EHPGDGAA
	SCHEMBL30431114	0.82	MAPT (0.44)	MAPTCYP3A4KDM4EHPGDGAA
	SCHEMBL548167	0.79	ERN1 (0.42)	MAPTCYP3A4KDM4EHPGDHSD17B10
	SCHEMBL27814250	0.78	KDM4E (0.50)	MAPTCYP3A4KDM4EALDH1A1LMNA
	SCHEMBL547605	0.77	CYP3A4 (0.35)	MAPTCYP3A4KDM4EALDH1A1TDP1
	SCHEMBL31121587	0.76	MAPT (0.40)	MAPTCYP3A4KDM4EHPGDGAA
	SCHEMBL5552901	0.76	ALDH1A1 (0.45)	MAPTCYP3A4KDM4EHPGDGAA
	SCHEMBL1174688	0.74	TPMT (0.50)	MAPTCYP3A4KDM4EHPGDHSD17B10
	SCHEMBL18239280	0.72	KDM4E (0.42)	MAPTCYP3A4KDM4EHPGDGAA
	SCHEMBL235710	0.71	KDM4E (0.54)	KDM4EHPGDGAAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.