SCHEMBL547710

SCHEMBL547710

O=C(O)CN[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 2/20 0.55
MME P08473 2/20 0.54
NPSR1 Q6W5P4 1/20 0.53
CYP1A2 P05177 1/20 0.52
MMP2 P08253 3/20 0.50
MMP9 P14780 2/20 0.50
CPA1 P15085 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
FOLH1 Q04609 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272029 1.00 NAALAD2 (0.55) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL547297 1.00 NAALAD2 (0.55) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL9340320 0.98 NAALAD2 (0.54) NAALAD2MMENPSR1CYP1A2MMP2
Ethylene SCHEMBL27880834 0.96 NAALAD2 (0.53) NAALAD2MMENPSR1CYP1A2MMP2
Sulfuric Acid SCHEMBL1507951 0.93 MMP2 (0.52) NAALAD2MMENPSR1MMP2MMP9
SCHEMBL23925862 0.87 MME (0.56) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL1921156 0.87 MME (0.56) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL1921155 0.87 MME (0.56) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL11719909 0.86 MME (0.51) NAALAD2MMENPSR1CYP1A2MMP2
SCHEMBL596492 0.86 NAALAD2 (0.53) NAALAD2MMENPSR1CYP1A2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP claimed
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP disclosed
EP-2604697-B1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) 2015-07-01 EP disclosed
US-8883462-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2014-11-11 US disclosed
EP-2000540-B1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) 2014-05-14 EP disclosed
EP-2604697-A1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer Tokyo University of Agriculture and Technology TLO (JP) 2013-06-19 EP disclosed
EP-2508611-A1 Process for production of triprenyl phenol compounds Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2012-10-10 EP disclosed
US-20120100579-A1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-04-26 US disclosed
US-8110596-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-02-07 US disclosed
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2009-08-27 US disclosed
EP-2000540-A9 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2009-03-25 EP disclosed
EP-2000540-A2 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer PLAT, F2R, F12 NAALAD2 1047/4885MME 43/4885NPSR1 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.