Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272029 | 0.98 | NAALAD2 (0.55) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| SCHEMBL547297 | 0.98 | NAALAD2 (0.55) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| SCHEMBL547710 | 0.98 | NAALAD2 (0.55) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| Ethylene SCHEMBL27880834 | 0.95 | NAALAD2 (0.53) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| Sulfuric Acid SCHEMBL1507951 | 0.92 | MMP2 (0.52) | NAALAD2MMENPSR1MMP2MMP9 | |
| SCHEMBL23925862 | 0.85 | MME (0.56) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| SCHEMBL1921156 | 0.85 | MME (0.56) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| SCHEMBL1921155 | 0.85 | MME (0.56) | NAALAD2MMENPSR1CYP1A2MMP2 | |
| SCHEMBL7597828 | 0.84 | NAALAD2 (0.57) | NAALAD2MMEL3MBTL1FOLH1 | |
| SCHEMBL11719909 | 0.84 | MME (0.51) | NAALAD2MMENPSR1CYP1A2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332452-B1 | Automated synthesizing apparatus | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5316728-A | Automated synthesizing apparatus | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-31 | — | — | US | disclosed |
| US-5164159-A | For modified amino acids | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0332452-A1 | Automated synthesizing apparatus | Takeda Chemical Industries, Ltd. (JP) | 1989-09-13 | — | — | EP | disclosed |