Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478284 | 0.89 | TRPV1 (0.67) | TRPV1MAPK3 | |
| SCHEMBL5475226 | 0.88 | TRPV1 (0.62) | TRPV1MAPK3 | |
| SCHEMBL5481611 | 0.86 | TRPV1 (0.59) | TRPV1EPHX2MAPK3 | |
| SCHEMBL5472643 | 0.80 | TRPV1 (0.52) | TRPV1EPHX2 | |
| SCHEMBL5479634 | 0.77 | TRPV1 (0.78) | TRPV1MAPK3 | |
| SCHEMBL5479119 | 0.76 | TRPV1 (0.62) | TRPV1MAPK3 | |
| SCHEMBL5477967 | 0.74 | TRPV1 (0.76) | TRPV1MAPK3 | |
| SCHEMBL1858141 | 0.74 | TRPV1 (0.50) | TRPV1PTGESMAPK3 | |
| SCHEMBL5477985 | 0.74 | TRPV1 (0.62) | TRPV1MAPK3 | |
| SCHEMBL5485574 | 0.73 | TRPV1 (0.62) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | CNR1, GPR174, CNR2 | TRPV1 379/4885EPHX2 2765/4885PTGES 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.