Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.59 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477967 | 0.89 | TRPV1 (0.76) | TRPV1MAPK3 | |
| SCHEMBL5477985 | 0.88 | TRPV1 (0.62) | TRPV1MAPK3 | |
| SCHEMBL5477296 | 0.86 | TRPV1 (0.52) | TRPV1MAPK3EPHX2 | |
| SCHEMBL5477068 | 0.84 | TRPV1 (0.62) | TRPV1MAPK3 | |
| SCHEMBL5472596 | 0.82 | TRPV1 (0.66) | TRPV1MAPK3 | |
| SCHEMBL4678015 | 0.82 | TRPV1 (0.51) | TRPV1EPHX2 | |
| SCHEMBL5485574 | 0.80 | TRPV1 (0.62) | TRPV1EPHX2 | |
| SCHEMBL4359111 | 0.79 | TRPV1 (0.54) | TRPV1MAPK3EPHX2 | |
| SCHEMBL14441331 | 0.77 | TRPV1 (0.59) | TRPV1MAPK3 | |
| SCHEMBL5479281 | 0.77 | TRPV1 (0.78) | TRPV1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | NEUROGEN COROPERATION (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191374-A1 | Substituted cinnolin-4-ylamines | CNR1, GPR174, CNR2 | TRPV1 379/4885MAPK3 3724/4885EPHX2 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.