SCHEMBL547788

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28521052	0.98	SOS1 (0.50)	SOS1ALDH1A1HPGDKDM4EGLA
	SCHEMBL28906694	0.83	CYP2D6 (0.51)	ALDH1A1HPGDKDM4EGLAWDR5
	SCHEMBL10946505	0.80	MEN1 (0.65)	SOS1ALDH1A1HPGDKDM4EGLA
	SCHEMBL547877	0.78	WDR5 (0.61)	ALDH1A1HPGDKDM4EGLAGAA
	SCHEMBL547541	0.78	IDO1 (0.47)	ALDH1A1HPGDKDM4EGLAGAA
	SCHEMBL547664	0.77	ERN1 (0.49)	ALDH1A1HPGDGAAMEN1KMT2A
	SCHEMBL10348819	0.76	ERN1 (0.56)	SOS1ALDH1A1HPGDGAAERN1
	SCHEMBL25256056	0.76	HSD17B10 (0.52)	ALDH1A1HPGDKDM4EWDR5MEN1
	SCHEMBL547570	0.76	IDO1 (0.46)	ALDH1A1HPGDKDM4EGLAGAA
	SCHEMBL548199	0.76	IDO1 (0.46)	ALDH1A1HPGDKDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.