Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477929 | 0.88 | — | — | |
| SCHEMBL5478487 | 0.87 | TDP1 (0.38) | TDP1MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL5478468 | 0.86 | CYP3A4 (0.39) | TDP1MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL5482715 | 0.72 | CA12 (0.46) | TDP1MEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL18635926 | 0.72 | CASP1 (0.34) | TDP1CYP3A4ALDH1A1TSHRTP53 | |
| SCHEMBL5480328 | 0.72 | APP (0.38) | MEN1KMT2ACYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL5481650 | 0.70 | — | — | |
| SCHEMBL5477932 | 0.70 | APP (0.38) | TDP1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5476090 | 0.69 | — | — | |
| Ethane SCHEMBL1599237 | 0.69 | TDP1 (0.88) | TDP1MEN1KMT2AKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032556-A1 | Aromatic polyamine derivative | DAICEL CHEMICAL INSUSTRIES, LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032556-A1 | Aromatic polyamine derivative | SRM, PRMT1, KDM8 | TDP1 1132/4885MEN1 1236/4885KMT2A 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.