SCHEMBL5478697

SCHEMBL5478697

c1ccc(-c2nnc(-c3ccccn3)[nH]2)nc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.59
LMNA P02545 6/20 0.59
METAP1 P53582 5/20 0.59
CCR1 P32246 2/20 0.59
CCR5 P51681 2/20 0.59
CCR8 P51685 2/20 0.59
HIF1A Q16665 2/20 0.59
CYP1A2 P05177 1/20 0.59
POLB P06746 1/20 0.59
BLM P54132 1/20 0.59
DOHH Q9BU89 1/20 0.59
P4HTM Q9NXG6 1/20 0.59
BTK Q06187 1/20 0.57
NPC1 O15118 8/20 0.56
RAB9A P51151 8/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
PKM P14618 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
TP53 P04637 3/20 0.56
ALOX15 P16050 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014813 0.92 SMN1; SMN2 (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL12438899 0.90 NPY5R (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL420934 0.86 KDM4E (0.54) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL18465753 0.86 BTK (0.49) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL3705717 0.86 BTK (0.49) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL30808597 0.86 BTK (0.49) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL8628220 0.86 BTK (0.49) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL9111577 0.84 NPY5R (0.45) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL28205258 0.84 METAP1 (0.50) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL23222296 0.82 METAP1 (0.47) KDM4ELMNAMETAP1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6278056-B1 ELECTRODE HAVING ADSORBED METAL COMPLEX HAVING LIGANDS OF 1,10-PHENANTHROLINE-4-CARBOXYLIC OR-4-7-DICARBOXYLIC ACID OR AND A NITROGEN-CONTAINING POLYCYCLIC THIN FILM; ABSORBS SOLAR LIGHT AND HIGH PHOTOELECTRIC TRANSFER DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2001-08-21 US claimed
US-8064119-B2 Display element and driving method thereof KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-22 US disclosed
WO-2011035064-A2 TRIAZOLE CATALYSTS AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2011-03-24 WO disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100091352-A1 DISPLAY ELEMENT AND DRIVING METHOD THEREOF KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20100091352-A1 DISPLAY ELEMENT AND DRIVING METHOD THEREOF KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20070296329-A1 Metal Complex, Luminescent Solid, Organic El Element and Organic El Display FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-20070296329-A1 Metal Complex, Luminescent Solid, Organic El Element and Organic El Display FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-20070296329-A1 Metal Complex, Luminescent Solid, Organic El Element and Organic El Display FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070296329-A1 Metal Complex, Luminescent Solid, Organic El Element and Organic El Display ELP1, LEF1, SLC39A14 KDM4E 1825/4885LMNA 3317/4885METAP1 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.