Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 5/20 | 0.50 |
| ▸ | METAP2 | P50579 | 4/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.50 |
| ▸ | CBFB | Q13951 | 3/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438899 | 0.86 | NPY5R (0.59) | METAP1METAP2TGFBR1NPY5RAURKA | |
| SCHEMBL5478697 | 0.84 | KDM4E (0.59) | METAP1METAP2NPY5RBTKNPC1 | |
| SCHEMBL9111577 | 0.83 | NPY5R (0.45) | METAP1METAP2MAPK14NPY5RAURKA | |
| SCHEMBL28043674 | 0.83 | CBFB (0.53) | METAP2TGFBR1CBFBMAPK14NPY5R | |
| SCHEMBL11135466 | 0.82 | NPC1 (0.53) | METAP1METAP2TGFBR1CBFBMAPK14 | |
| SCHEMBL21067971 | 0.80 | NPC1 (0.52) | MAPK14NPY5RBTKNPC1RAB9A | |
| SCHEMBL416443 | 0.80 | METAP2 (0.53) | METAP1METAP2CBFBNPY5RAURKA | |
| SCHEMBL9109396 | 0.80 | NPY5R (0.42) | METAP1METAP2CBFBNPY5RAURKA | |
| SCHEMBL19611704 | 0.78 | TGFBR1 (0.57) | TGFBR1NPY5RNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29638126 | 0.78 | TGFBR1 (0.57) | METAP1TGFBR1MAPK14FLT3DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085579-B | N hexyl carbazole substituted-phenyl benzothiazole iridium (III) complexs and its preparation | 太原理工大学 | 2018-03-27 | — | — | CN | disclosed |
| CN-105085579-A | N-hexyl carbazole substituted phenyl benzothiazole iridium (III) complex and preparation thereof | UNIV TAIYUAN TECHNOLOGY | 2015-11-25 | — | — | CN | disclosed |