Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477823 | 0.94 | AKR1C3 (0.39) | AKR1C3AKR1C2GAAALKALDH1A1 | |
| SCHEMBL5479004 | 0.87 | AKR1C3 (0.39) | AKR1C3AKR1C2GAAALKALDH1A1 | |
| SCHEMBL14583072 | 0.86 | AKR1C3 (0.40) | AKR1C3AKR1C2GAAALKALDH1A1 | |
| SCHEMBL5473603 | 0.85 | AKR1C3 (0.44) | AKR1C3AKR1C2GAAALDH1A1TDP1 | |
| SCHEMBL5480337 | 0.84 | AKR1C3 (0.42) | AKR1C3AKR1C2GAAALDH1A1TDP1 | |
| SCHEMBL5475416 | 0.78 | NPC1 (0.36) | GAAALDH1A1MAPTKDM4EGLA | |
| SCHEMBL21698312 | 0.76 | CXCR2 (0.48) | AKR1C3AKR1C2GAAALDH1A1TDP1 | |
| SCHEMBL5478515 | 0.73 | S100B (0.42) | GAAALKALDH1A1TDP1ALOX15 | |
| SCHEMBL5478509 | 0.73 | S100B (0.42) | GAAALKALDH1A1TDP1ALOX15 | |
| SCHEMBL11813158 | 0.73 | HSD17B10 (0.50) | AKR1C3AKR1C2GAAALKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032556-A1 | Aromatic polyamine derivative | DAICEL CHEMICAL INSUSTRIES, LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032556-A1 | Aromatic polyamine derivative | SRM, PRMT1, KDM8 | AKR1C3 201/4885AKR1C2 221/4885GAA 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.