Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480121 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2 | |
| SCHEMBL4718508 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5476585 | 0.99 | SLC6A4 (0.58) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5476579 | 0.99 | SLC6A4 (0.58) | SLC6A4SLC6A2 | |
| SCHEMBL4829654 | 0.90 | SLC6A4 (0.50) | SLC6A4SLC6A2 | |
| SCHEMBL4719212 | 0.83 | SLC6A2 (0.66) | SLC6A4SLC6A2 | |
| SCHEMBL5480035 | 0.83 | SLC6A2 (0.66) | SLC6A4SLC6A2 | |
| SCHEMBL5480039 | 0.83 | SLC6A2 (0.66) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5476683 | 0.82 | SLC6A2 (0.64) | SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5476678 | 0.82 | SLC6A2 (0.64) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041023-A1 | 1- (1H- INDOL- 1-YL) -3- (METHYLAMINO) -1- PHENYLPROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | WYETH (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | COMT, PNMT, GLS | SLC6A4 16/4885SLC6A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.