Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480638 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4716801 | 0.91 | SLC6A2 (0.43) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4716804 | 0.91 | SLC6A2 (0.43) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL5476112 | 0.91 | SLC6A4 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL4718277 | 0.91 | SLC6A4 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL4081757 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4081758 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4719054 | 0.88 | SLC6A2 (0.45) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4719051 | 0.88 | SLC6A2 (0.45) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4077295 | 0.85 | SLC6A2 (0.61) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | COMT, PNMT, GLS | SLC6A2 8/4885SLC6A4 16/4885ALDH1A1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.