Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468452 | 0.87 | TLR8 (0.45) | TLR8CXCR4CXCR3LMNA | |
| SCHEMBL5473914 | 0.86 | PRMT5 (0.49) | TLR8CXCR4ALDH1A1DYRK1ACXCR3 | |
| SCHEMBL5465854 | 0.81 | TLR8 (0.66) | TLR8CXCR4POLBCYP1A2CYP2D6 | |
| SCHEMBL5453372 | 0.80 | TLR8 (0.41) | TLR8ALDH1A1POLBCXCR3CYP1A2 | |
| SCHEMBL5454116 | 0.78 | POLB (0.58) | TLR8CXCR4POLBCYP1A2CYP2D6 | |
| SCHEMBL5480691 | 0.77 | MTNR1A (0.55) | TLR8ALDH1A1POLBMTNR1AMTNR1B | |
| SCHEMBL5453997 | 0.77 | TLR8 (0.53) | TLR8CXCR4ALDH1A1POLBLMNA | |
| SCHEMBL5451191 | 0.75 | CYP1A2 (0.56) | TLR8CXCR4ALDH1A1POLBCYP1A2 | |
| SCHEMBL14373235 | 0.74 | PRMT5 (0.43) | TLR8CXCR4ALDH1A1CXCR3HTT | |
| SCHEMBL5463793 | 0.74 | TLR8 (0.49) | TLR8ALDH1A1POLBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | TLR8 3837/4885CXCR4 3445/4885ALDH1A1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.