Benalaxyl

Benalaxyl

SCHEMBL54808

COC(=O)[C@H](C)N(C(=O)Cc1ccccc1)c1c(C)cccc1C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
PLA2G1B P04054 1/20 0.61
HTT P42858 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ATG4B Q9Y4P1 1/20 0.61
TRPM8 Q7Z2W7 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.44
RORC P51449 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benalaxyl SCHEMBL21674 1.00 KMT2A (0.61) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL8818251 1.00 KMT2A (0.61) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL2528870 1.00 KMT2A (0.61) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL41642 1.00 KMT2A (0.61) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL7182610 0.99 KMT2A (0.60) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL27822944 0.99 KMT2A (0.60) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL10379769 0.94 MEN1 (0.55) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL6406729 0.94 KMT2A (0.55) KMT2AMEN1PLA2G1BHTTNPSR1
SCHEMBL14384723 0.93 MEN1 (0.57) KMT2AMEN1PLA2G1BHTTNPSR1
Benalaxyl SCHEMBL28703732 0.93 MEN1 (0.54) KMT2AMEN1PLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 911 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
EP-2563138-A1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE Sumitomo Chemical Company Limited (JP) 2013-03-06 EP claimed
US-20130053424-A1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-28 US claimed
WO-2011135836-A1 Plant disease control composition and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 WO claimed
US-20100197495-A1 Synergistic Mixtures and/or Compositions With a High Fungicidal Activity ISAGRO S.P.A. (IT) 2010-08-05 US claimed
EP-1912506-A2 SYNERGISTIC MIXTURES AND/OR COMPOSITIONS WITH A HIGH FUNGICIDAL ACTIVITY ISAGRO S.p.A. (IT) 2008-04-23 EP claimed
WO-2007017220-A2 SYNERGISTIC MIXTURES AND/OR COMPOSITIONS WITH A HIGH FUNGICIDAL ACTIVITY ISAGRO S.P.A. (IT) 2007-02-15 WO claimed
US-20060159772-A1 Fungicidal compositions ISAGRO S.P.A. (IT) 2006-07-20 US claimed
US-20050255171-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. 2005-11-17 US claimed
EP-1565057-A2 FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT ISAGRO S.p.A. (IT) 2005-08-24 EP claimed
US-20030055096-A1 Fungicidal composition OGURI YUKIO (JP) 2003-03-20 US claimed
EP-0979034-B1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA (JP) 2003-02-26 EP claimed
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. 2002-10-03 US claimed
EP-1028125-A1 Dipeptide compounds having fungicidal activity and their agronomic use Isagro Ricerca S.r.l. (IT) 2000-08-16 EP claimed
JP-2582885-B2 1997-02-19 JP claimed
EP-0741970-A1 BACTERICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-13 EP claimed
EP-0193922-B1 FUNGICIDAL AND PLANT GROWTH REGULATING AGENTS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1992-03-11 EP claimed
EP-0305442-A1 FUNGICIDE COMPOSITIONS. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1989-03-08 EP claimed
WO-1988006841-A1 FUNGICIDE COMPOSITIONS Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1988-09-22 WO claimed
EP-0193922-A2 Fungicidal and plant growth regulating agents CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1986-09-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053424-A1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE AADAT, NAT1, AADAC KMT2A 12/4885MEN1 2328/4885PLA2G1B 1666/4885
US-20050255171-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same IPMK, PPA1, ERG28 KMT2A 4046/4885MEN1 302/4885PLA2G1B 1998/4885
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same PPA1, IPMK, ERG28 KMT2A 4153/4885MEN1 261/4885PLA2G1B 2276/4885
US-20030055096-A1 Fungicidal composition CBR1, CBR3, CYP1B1 KMT2A 2342/4885MEN1 1994/4885PLA2G1B 4233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.