Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111243 | 0.86 | MIF (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29846915 | 0.86 | MIF (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL18263455 | 0.85 | TAAR1 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6961980 | 0.81 | MIF (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL325486 | 0.80 | IDO1 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1852165 | 0.78 | TAAR1 (0.47) | TAAR1HIF1AGABRA1GABRB2 | |
| SCHEMBL1847891 | 0.78 | IDO1 (0.46) | IDO1DAOPYCR1 | |
| SCHEMBL28850568 | 0.78 | DPP4 (0.46) | HIF1A | |
| SCHEMBL1845576 | 0.77 | TAAR1 (0.48) | TAAR1IDO1PYCR1HIF1AGABRA1 | |
| SCHEMBL11253674 | 0.77 | TAAR1 (0.48) | TAAR1DAOCTBP2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102170883-A | Compounds useful as inhibitors of protein kinases | ABBOTT LAB | 2011-08-31 | — | — | CN | disclosed |
| US-20070275967-A1 | Pyrazolinols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-29 | — | — | US | disclosed |
| CN-1894218-A | Pyrazolines as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-01-10 | — | — | CN | disclosed |
| EP-1697328-A1 | PYRAZOLINOLS USED AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058838-A1 | PYRAZOLINOLS USED AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275967-A1 | Pyrazolinols | RRS1, RECQL, PNISR | HTR3E 3541/4885HTR3B 3098/4885HTR3A 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.