Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332409 | 0.86 | MIF (0.65) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL5480950 | 0.81 | HTR3E (0.53) | HIF1AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8763654 | 0.80 | MIF (0.59) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL1457250 | 0.80 | MIF (0.52) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL10434109 | 0.77 | MIF (0.55) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL5357568 | 0.77 | MIF (0.55) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL7525986 | 0.74 | KEAP1 (0.53) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL331146 | 0.74 | MIF (0.68) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL5540201 | 0.74 | TAAR1 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6740216 | 0.73 | TAAR1 (0.71) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |