Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 4/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550734 | 0.94 | RNASE1 (0.43) | RNASE1TK1TK2 | |
| SCHEMBL8659511 | 0.93 | TYMS (0.41) | RNASE1TK1TK2TYMS | |
| SCHEMBL8656814 | 0.92 | RNASE1 (0.39) | RNASE1TK1TK2TYMS | |
| SCHEMBL8656850 | 0.91 | RNASE1 (0.42) | RNASE1TK1TK2 | |
| SCHEMBL9017734 | 0.90 | RNASE1 (0.38) | RNASE1TK1TK2TOP2A | |
| SCHEMBL8656110 | 0.90 | RNASE1 (0.39) | RNASE1TK1TK2TOP2A | |
| SCHEMBL8658180 | 0.85 | RNASE1 (0.44) | RNASE1TK1TK2TYMS | |
| SCHEMBL8658448 | 0.83 | RNASE1 (0.43) | RNASE1TK1TK2 | |
| SCHEMBL8654714 | 0.82 | RNASE1 (0.43) | RNASE1TK1TK2 | |
| SCHEMBL13939944 | 0.82 | TK1 (0.41) | RNASE1TK1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783216-A1 | TELOMERASE-INHIBITORY ENA OLIGONUCLEOTIDE | Sankyo Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |