Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.67 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.67 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.67 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741346 | 0.98 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBKDR | |
| SCHEMBL16487356 | 0.98 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBKDR | |
| SCHEMBL9668597 | 0.95 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBKDR | |
| SCHEMBL19686245 | 0.89 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBKDR | |
| SCHEMBL7211994 | 0.86 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6029471 | 0.84 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL27761904 | 0.82 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL5066797 | 0.82 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6683145 | 0.80 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL4551802 | 0.80 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070059740-A1 | METHOD OF TARGETING A2B ADENOSINE RECEPTOR ANTAGONIST THERAPY | UNIVERSITY OF VIRGINIA | 2007-03-15 | — | — | US | claimed |
| US-20070059740-A1 | METHOD OF TARGETING A2B ADENOSINE RECEPTOR ANTAGONIST THERAPY | UNIVERSITY OF VIRGINIA | 2007-03-15 | — | — | US | disclosed |