Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 6/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686245 | 0.86 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL9668597 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL5481178 | 0.82 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL27741346 | 0.80 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16487356 | 0.80 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5848451 | 0.80 | ADORA3 (0.41) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL6683145 | 0.80 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL6029471 | 0.77 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL669406 | 0.77 | ADORA2A (0.40) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL18757974 | 0.76 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343119-A | Preparation method of alkylated nucleoside, nucleotide, oligonucleotide and analogues thereof | 上海交通大学 | 2024-01-05 | — | — | CN | disclosed |
| WO-2017153527-A1 | NOVEL INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE GAMMA | ASTRAZENECA AB (SE) | 2017-09-14 | — | — | WO | disclosed |
| CN-104478883-B | A kind of C8-Heterocyclylalkyl purine nucleoside analogs and synthetic method thereof | HENAN SCIENCE AND TECHNOLOGY COLLEGE (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104478883-A | Novel C8-heterocyclic alkylated purine nucleoside analogue and synthetic method thereof | HENAN INST SCIENCE & TECH | 2015-04-01 | — | — | CN | disclosed |
| US-8268849-B2 | Multifunctional Antioxidants and methods of use thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268849-B2 | Multifunctional Antioxidants and methods of use thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-09-18 | — | — | US | disclosed |
| US-8172873-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110251364-A1 | Shape Memory Polymers | NATIONAL SCIENCE FOUNDATION | 2011-10-13 | — | — | US | disclosed |
| US-7935131-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090105269-A1 | Multifunctional Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-23 | — | — | US | disclosed |
| US-20090105269-A1 | Multifunctional Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-23 | — | — | US | disclosed |
| US-20080177303-A1 | Shape memory polymers | ROCHESTER, UNIVERSITY OF | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105269-A1 | Multifunctional Compounds and Methods of Use Thereof | AS3MT, OAT, NCL | PI4KA 2959/4885PI4K2B 2361/4885PI4K2A 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.