Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 6/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029471 | 0.90 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL7211994 | 0.88 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL19686245 | 0.84 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL9668597 | 0.81 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL5481178 | 0.80 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5066797 | 0.80 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL16487356 | 0.79 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL27741346 | 0.79 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL669406 | 0.76 | ADORA2A (0.40) | PI4KAPI4K2BPI4K2API4KBNUDT1 | |
| SCHEMBL11909745 | 0.76 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069854-A1 | NOVEL ANHYDROLIDE DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | ENANTA PHARMACEUTICALS. INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-1313751-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016380-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2002-02-28 | — | — | WO | disclosed |