Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152966 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| Butadiene SCHEMBL2729309 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| Styrene SCHEMBL8466307 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| Styrene SCHEMBL9124799 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL2339418 | 0.82 | LMNA (0.44) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL9066552 | 0.82 | AKR1C3 (0.47) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL6061065 | 0.82 | MCL1 (0.43) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL29885801 | 0.82 | MCL1 (0.43) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL11300877 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL7006805 | 0.79 | KDM4E (0.56) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010635-A1 | Low gloss thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-01-11 | — | — | US | disclosed |