Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | SMO | Q99835 | 8/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485509 | 0.91 | MAPK14 (0.49) | PARP10MAPK14SMOKCNH2KDM4E | |
| SCHEMBL14534447 | 0.88 | ALDH1A1 (0.51) | PARP10MAPK14SMOKCNH2KDM4E | |
| SCHEMBL5489925 | 0.88 | PARP10 (0.48) | PARP10MAPK14SMOKCNH2KDM4E | |
| SCHEMBL4408195 | 0.85 | PARP10 (0.48) | PARP10MAPK14SMOSIRT2SIRT3 | |
| SCHEMBL5480560 | 0.82 | MEN1 (0.52) | MAPK14SMOKCNH2NPC1RAB9A | |
| SCHEMBL5487370 | 0.82 | MAPK14 (0.44) | PARP10MAPK14SMOKCNH2 | |
| SCHEMBL4416216 | 0.82 | MAPK14 (0.53) | MAPK14SMOKCNH2 | |
| SCHEMBL14534467 | 0.80 | NR1H4 (0.49) | MAPK14SMOKCNH2 | |
| SCHEMBL4415122 | 0.80 | MAPK14 (0.69) | MAPK14SMO | |
| SCHEMBL14534669 | 0.80 | MAPK14 (0.44) | PARP10MAPK14SMOKCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |