Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | SMO | Q99835 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481396 | 0.88 | PARP10 (0.58) | PARP10MAPK14SMONPC1PKM | |
| SCHEMBL14534453 | 0.88 | PARP10 (0.43) | PARP10MAPK14SMOSMN1; SMN2KDM4E | |
| SCHEMBL5485509 | 0.87 | MAPK14 (0.49) | PARP10MAPK14SMONPC1PKM | |
| SCHEMBL14534447 | 0.84 | ALDH1A1 (0.51) | PARP10MAPK14SMONPC1PKM | |
| SCHEMBL5480560 | 0.84 | MEN1 (0.52) | MAPK14SMONPC1RAB9AMAPT | |
| SCHEMBL14534669 | 0.83 | MAPK14 (0.44) | PARP10MAPK14SMOSMN1; SMN2MAPT | |
| SCHEMBL4416216 | 0.82 | MAPK14 (0.53) | MAPK14SMOMAPTKCNH2 | |
| SCHEMBL4415122 | 0.80 | MAPK14 (0.69) | MAPK14SMOMAPT | |
| SCHEMBL4408195 | 0.80 | PARP10 (0.48) | PARP10MAPK14SMOSMN1; SMN2MAPT | |
| SCHEMBL1922125 | 0.79 | PRKCI (0.52) | NPC1RAB9ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |