Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5164193 | 1.00 | MEN1 (0.63) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Miramistin Ion SCHEMBL2236560 | 1.00 | MEN1 (0.63) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Miramistin Ion SCHEMBL17530472 | 0.99 | MEN1 (0.64) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL11305761 | 0.99 | DNM1 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL10034064 | 0.99 | DNM1 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Miramistin Ion SCHEMBL2238282 | 0.99 | DNM1 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Miramistin Ion SCHEMBL23922700 | 0.97 | MEN1 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28383398 | 0.93 | EPHX2 (0.65) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL7091153 | 0.92 | EPHX2 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL7089077 | 0.92 | EPHX2 (0.62) | MEN1KMT2ATP53MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117065937-A | Low-grade lepidolite flotation combined collector and application thereof | 东北大学 | 2023-11-17 | — | — | CN | disclosed |
| US-20070298346-A1 | Toner particles of controlled morphology | EASTMAN KODAK COMPANY | 2007-12-27 | — | — | US | disclosed |
| WO-2007149461-A2 | TONER PARTICLES OF CONTROLLED MORPHOLOGY | EASTMAN KODAK COMPANY (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20030224280-A1 | Process for lowering charge/mass ratio of toner particles having controlled morphology and containing quaternary ammonium tetraphenylborate charge control agents | HEIDELBERG DIGITAL L.L.C. | 2003-12-04 | — | — | US | disclosed |
| US-20030008227-A1 | Method for forming toner particles having controlled morphology and containing quaternary ammonium tetraphenylborate charge control agents | EASTMAN KODAK COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-6416921-B1 | FORMING NON-SPHERICAL TONER PARTICLES USING LIMITED COALESCENSE; IMPROVED TRANSFER AND CLEANING EFFICIENCY | HEIDELBERG DIGITAL L.L.C. | 2002-07-09 | — | — | US | disclosed |