Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477677 | 0.95 | MEN1 (0.33) | MAOAMAOBMEN1PABPC1KMT2A | |
| SCHEMBL5484884 | 0.86 | AGTR1 (0.36) | MEN1PABPC1KMT2A | |
| SCHEMBL5472502 | 0.81 | MEN1 (0.37) | MEN1PABPC1KMT2A | |
| SCHEMBL5478609 | 0.78 | MEN1 (0.38) | MEN1PABPC1KMT2A | |
| SCHEMBL5484430 | 0.70 | MEN1 (0.41) | MEN1PABPC1KMT2A | |
| SCHEMBL13524686 | 0.65 | MEN1 (0.46) | MEN1PABPC1KMT2A | |
| SCHEMBL14989254 | 0.59 | KDM4C (0.39) | — | |
| SCHEMBL14989097 | 0.59 | KDM4C (0.39) | — | |
| SCHEMBL14989286 | 0.59 | KDM4C (0.39) | — | |
| SCHEMBL14989148 | 0.59 | KDM4C (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | claimed |
| EP-1798234-B1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | TIANJIN TASLY GROUP CO LTD (CN) | 2012-06-13 | — | — | EP | disclosed |
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | disclosed |