Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478609 | 0.80 | MEN1 (0.38) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL5472502 | 0.77 | MEN1 (0.37) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL5473280 | 0.74 | ADORA2A (0.40) | MEN1PABPC1KMT2A | |
| SCHEMBL5473765 | 0.73 | AGTR1 (0.36) | MEN1PABPC1KMT2A | |
| SCHEMBL5477677 | 0.72 | MEN1 (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL5481771 | 0.70 | MAOA (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL5481143 | 0.70 | MEN1 (0.34) | MEN1PABPC1KMT2A | |
| SCHEMBL5481140 | 0.70 | MEN1 (0.32) | MEN1PABPC1KMT2A | |
| SCHEMBL892401 | 0.67 | MEN1 (0.77) | MEN1PABPC1KMT2AHTTHCAR3 | |
| SCHEMBL3700954 | 0.66 | HTT (0.52) | MEN1PABPC1KMT2AHTTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798234-B1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | TIANJIN TASLY GROUP CO LTD (CN) | 2012-06-13 | — | — | EP | disclosed |
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | disclosed |