Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.54 |
| ▸ | NOS2 | P35228 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481779 | 1.00 | SLC6A4 (0.54) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| SCHEMBL5481780 | 1.00 | SLC6A4 (0.54) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5478089 | 0.99 | SLC6A4 (0.55) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5478084 | 0.99 | SLC6A4 (0.55) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5478091 | 0.99 | SLC6A4 (0.55) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| SCHEMBL5473701 | 0.90 | SLC6A4 (0.66) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5478668 | 0.89 | SLC6A4 (0.67) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 | |
| SCHEMBL6329889 | 0.89 | NOS2 (0.60) | SLC6A4NOS2SLC6A2CYP2D6POLB | |
| Hydrochloric Acid SCHEMBL6327619 | 0.87 | NOS2 (0.59) | SLC6A4NOS2SLC6A2CYP2D6POLB | |
| SCHEMBL5481278 | 0.87 | NOS2 (0.50) | SLC6A4NOS2SLC6A2CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | claimed |
| EP-1725518-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005092835-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ADRB3, HTR3C, SLC6A2 | SLC6A4 15/4885NOS2 514/4885SLC6A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.