Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL548182

CC.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.83

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.83
BLM P54132 1/20 0.83
TDP1 Q9NUW8 1/20 0.83
CA2 P00918 1/20 0.43
BTN3A1 O00481 4/20 0.39
CA4 P22748 1/20 0.35
INPPL1 O15357 2/20 0.33
INPP5A Q14642 2/20 0.33
SMPD1 P17405 1/20 0.33
INPP5B P32019 1/20 0.33
PPARD Q03181 1/20 0.33
ALDH1A1 P00352 1/20 0.33
BCHE P06276 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL3910021 1.00 FDPS (0.83) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL28456752 0.92 FDPS (0.83) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL27780224 0.92 FDPS (0.83) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL29634664 0.91
Pyrophosphoric Acid SCHEMBL3654 0.91
Pyrophosphoric Acid SCHEMBL8851914 0.91 FDPS (1.00) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL292348 0.91 FDPS (1.00) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL23537580 0.87 FDPS (0.91) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL596848 0.87 FDPS (0.91) FDPSBLMTDP1CA2BTN3A1
Pyrophosphoric Acid SCHEMBL57948 0.87 FDPS (0.91) FDPSBLMTDP1CA2BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0649441-A4 CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS. UNIV MICHIGAN (US) 1998-12-02 EP claimed
EP-0740683-A4 CALCIFICATION-RESISTANT BIOMATERIALS UNIV MICHIGAN (US) 1998-07-15 EP claimed
EP-0740683-A1 CALCIFICATION-RESISTANT BIOMATERIALS THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1996-11-06 EP claimed
WO-1995020008-A1 CALCIFICATION-RESISTANT BIOMATERIALS THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1995-07-27 WO claimed
US-5436291-A Biocompatible implant of polymer modified with polyphosphonate through epoxide linkage; cardiac valve prostheses; irreversible binding of anticalcification agent to biomaterial UNIVERSITY OF MICHIGAN, THE BOARD OF . . . (US) 1995-07-25 US claimed
EP-0649441-A1 CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS THE UNIVERSITY OF MICHIGAN (US) 1995-04-26 EP claimed
US-5368608-A Aluminum cations and polymer, biocompatible grafts UNIVERSITY OF MICHIGAN, THE BOARD OF REGENTS (US) 1994-11-29 US claimed
US-5296583-A Polyphosphonate-epoxide-urethane UNIVERSITY OF MICHIGAN (US) 1994-03-22 US claimed
WO-1994001481-A1 CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS UNIVERSITY OF MICHIGAN (US) 1994-01-20 WO claimed
EP-0236007-B1 PROCESS FOR THE PREPARATION OF OXODISUCCINATES USEFUL AS DETERGENT BUILDERS THE PROCTER & GAMBLE COMPANY (US) 1990-08-29 EP claimed
US-4753652-A Biomaterial implants which resist calcification CHILDREN'S MEDICAL CENTER CORPORATION (US) 1988-06-28 US claimed
WO-2024262353-A1 COMPOSITION FOR ORAL CAVITY ライオン株式会社 2024-12-26 WO disclosed
CN-118201583-A Cleansing bar and compositions thereof 联合利华知识产权控股有限公司 2024-06-14 CN disclosed
CN-116322615-A Cleaning composition comprising a mixture of fatty acids and soaps and method for preparing a cleaning bar comprising the mixture 联合利华知识产权控股有限公司 2023-06-23 CN disclosed
US-20230190578-A1 REVERSIBLE IMMOBILIZATION AND/OR CONTROLLED RELASE OF NUCLEIC ACID CONTAINING NANOPARTICLES BY (BIODEGRADABLE) POLYMER COATINGS CureVac SE (DE) 2023-06-22 US disclosed
EP-0047983-B1 RADIOACTIVE DIAGNOSTIC AGENT FOR BONE SCANNING AND NON-RADIOACTIVE CARRIER THEREFOR NIHON MEDI-PHYSICS CO., LTD. (JP) 1984-04-11 EP disclosed
US-4439413-A METHANEHYDROXYDIPHOSPHONIC ACID OR SALTS NIHON MEDI-PHYSICS COMPANY, LTD. (JP) 1984-03-27 US disclosed
EP-0028850-B1 LIQUID DETERGENT COMPOSITION UNILEVER N.V. (NL) 1983-04-20 EP disclosed
EP-0028850-A1 Liquid detergent composition UNILEVER N.V. (NL) 1981-05-20 EP disclosed
US-4020091-A TIN SALTS OF POLYPHOSPHONIC ACIDS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1977-04-26 US disclosed