Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941738 | 0.90 | AGTR2 (0.45) | OXTRAGTR2AGTR1MMP1MMP3 | |
| SCHEMBL4941744 | 0.90 | AGTR2 (0.45) | OXTRAGTR2AGTR1MMP1MMP3 | |
| SCHEMBL4942159 | 0.86 | AGTR2 (0.44) | OXTRAGTR2AGTR1MMP1MMP3 | |
| SCHEMBL4941413 | 0.85 | AGTR2 (0.41) | OXTRAGTR2AGTR1MMP1MMP3 | |
| SCHEMBL4941411 | 0.85 | AGTR2 (0.41) | OXTRAGTR2AGTR1MMP1MMP3 | |
| SCHEMBL4944243 | 0.85 | USP2 (0.45) | OXTRAGTR2KDM4EGAASMN1; SMN2 | |
| SCHEMBL4944248 | 0.85 | USP2 (0.45) | OXTRAGTR2KDM4EGAASMN1; SMN2 | |
| SCHEMBL4939973 | 0.81 | AGTR2 (0.43) | AGTR2GAAAGTR1 | |
| SCHEMBL4939969 | 0.81 | AGTR2 (0.43) | AGTR2GAAAGTR1 | |
| SCHEMBL4941922 | 0.78 | OXTR (0.54) | OXTRAVPR1ATDP1MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211601-B2 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-05-01 | — | — | US | claimed |