SCHEMBL5481879

SCHEMBL5481879

CN(S)C(=O)c1[c]cccc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
HPGD P15428 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160477 0.84 SMN1; SMN2 (0.40) KMT2AMEN1NPC1RAB9ACA12
SCHEMBL1642736 0.78 TRPM8 (0.38) KMT2AMEN1RAB9ATSHR
SCHEMBL8542716 0.78 POLB (0.49) KMT2ANPC1RAB9AALDH1A1TSHR
SCHEMBL7577039 0.78 TRPM8 (0.39) KMT2AMEN1NPC1RAB9ACA12
SCHEMBL8131195 0.76 NPSR1 (0.41) KMT2AMEN1CA12CA9ALDH1A1
SCHEMBL3563895 0.76 HPGD (0.47) KMT2ANPC1ALDH1A1TP53MAPT
SCHEMBL7849513 0.75 CHRM2 (0.38) KMT2AMEN1NPC1RAB9ACA12
SCHEMBL2478084 0.74 LMNA (0.36) ALDH1A1TP53MAPTTSHRHPGD
SCHEMBL6678143 0.73 NPSR1 (0.48) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL483123 0.73 TP53 (0.58) KMT2AMEN1CA12CA9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166411-B2 Photosensitive composition and planographic printing plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-01-23 US disclosed
EP-1382460-B1 Photosensitive composition and planographic printing plate using the same FUJI PHOTO FILM CO LTD (JP) 2005-12-28 EP disclosed
US-20040229156-A1 Photosensitive composition and planographic printing plate using the same FUJI PHOTO FILM CO,. LTD. (JP) 2004-11-18 US disclosed
EP-1382460-A1 Photosensitive composition and planographic printing plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2004-01-21 EP disclosed
US-6673510-B1 LITHOGRAPHY PLATES COMPRISING METHINE DYES AS INFRARED RADIATION ABSORBER MATERIALS AND AN ACRYLIC TERPOLYMERS WHICH IS INSOLUBLE IN WATER AND SOLUBLE IN ALKALI SOLUTION, WHEN HEATED USING LASERS FUJI PHOTO FILM CO., LTD. (JP) 2004-01-06 US disclosed
EP-1093934-A1 Photosensitive composition and planographic printing plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2001-04-25 EP disclosed