Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527492 | 0.93 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL4852920 | 0.92 | KDM4E (0.62) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL289044 | 0.90 | MAPT (0.74) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL475351 | 0.90 | MAPT (0.74) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL5065255 | 0.89 | KDM4E (0.65) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL4400710 | 0.88 | KDM4E (0.58) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL27645874 | 0.88 | MAPT (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL4335856 | 0.87 | KDM4E (0.62) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL28548565 | 0.86 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL4261073 | 0.85 | MAPT (0.67) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662154-B | Use the manufacture method of the lipid of thioesterase variant | 花王株式会社 | 2017-09-01 | — | — | CN | disclosed |
| US-20070141681-A1 | Process for the production of L-amino acids using strains of the Enterobacteriaceae family | DEGUSSA AG (DE) | 2007-06-21 | — | — | US | disclosed |
| US-7211415-B2 | Enterobacteriaceae strains over-expressing the yfiD gene for the fermentative production of L-amino acids | DEGUSSA AG (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20040235122-A1 | Process for the production of L-amino acids using strains of the enterobacteriaceae family | EVONIK OPERATIONS GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-0946729-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5888768-A | CULTURE PRODUCT; GENETIC ENGINEERING | ZYMOGENETICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998020133-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1998-05-14 | — | — | WO | disclosed |