Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021404 | 0.86 | ALDH1A1 (0.60) | ALDH1A1TSHRTHRBEPHX2HSD17B10 | |
| SCHEMBL9333278 | 0.86 | ALDH1A1 (0.60) | ALDH1A1TSHRTHRBEPHX2HSD17B10 | |
| SCHEMBL554266 | 0.86 | — | — | |
| SCHEMBL616408 | 0.84 | — | — | |
| SCHEMBL29061179 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TSHRTHRBEPHX2HSD17B10 | |
| SCHEMBL29061180 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBEPHX2HSD17B10 | |
| SCHEMBL8504058 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRTHRBEPHX2 | |
| SCHEMBL9194711 | 0.77 | ALDH1A1 (0.74) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| SCHEMBL9447590 | 0.77 | CES2 (0.48) | ALDH1A1TSHRTHRBTP53 | |
| SCHEMBL8506799 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBEPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7270801-B2 | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1026988-A4 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA INC (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040191844-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-6759207-B2 | REPORTER COMPOUND FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF CANCER | CYTOVIA, INC. | 2004-07-06 | — | — | US | disclosed |
| US-20020150885-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6342611-B1 | BLOCKED RHODAMINE DERIVATIVES | CYTOVIA, INC. | 2002-01-29 | — | — | US | disclosed |
| US-6335429-B1 | COMPOUND INCLUDING SUBSTRATE FOR ENZYME AND RHODAMINE DYE; DRUG SCREENING FOR ANTICARCINOGENIC AGENTS | CYTOVIA, INC. | 2002-01-01 | — | — | US | disclosed |
| CN-1281346-A | Novel fluorescent reporter molecules and their applications, including assays for caspases | CYTOVIA INC (US) | 2001-01-24 | — | — | CN | disclosed |
| EP-1026988-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | Cytovia, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018856-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA, INC. (US) | 1999-04-22 | — | — | WO | disclosed |