Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | PRKACA | P17612 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125031 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4125061 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4137491 | 0.78 | CYP11B2 (0.41) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4125421 | 0.78 | CYP11B2 (0.39) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL5488685 | 0.78 | L3MBTL1 (0.36) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4130964 | 0.78 | CYP11B2 (0.38) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL13905028 | 0.77 | CYP11B2 (0.42) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4118354 | 0.77 | CYP11B2 (0.42) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL6400154 | 0.75 | CYP11B2 (0.40) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4505966 | 0.75 | L3MBTL1 (0.36) | KDM4EALDH1A1MAPTGFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007501189-A | — | — | 2007-01-25 | — | — | JP | claimed |
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | claimed |