SCHEMBL5482172

SCHEMBL5482172

CC(C)(C)NC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2B P18089 2/20 0.50
ADRA1A P35348 2/20 0.50
HRH1 P35367 2/20 0.50
OPRK1 P41145 2/20 0.50
SLC6A3 Q01959 2/20 0.50
KCNH2 Q12809 2/20 0.50
CACNA1C Q13936 2/20 0.50
SCN5A Q14524 2/20 0.50
CACNA1F O60840 1/20 0.50
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
CACNA1D Q01668 1/20 0.50
CACNA1S Q13698 1/20 0.50
HTT P42858 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
NCOA1 Q15788 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13676380 0.90 SMN1; SMN2 (0.45) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL13900807 0.80 CACNA1F (0.53) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL13950534 0.80 CACNA1F (0.53) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL12201552 0.80 CACNA1F (0.53) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL10245495 0.78 RIPK1 (0.54) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL7751173 0.78 RIPK1 (0.54) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL21799478 0.78 SLC6A3 (0.52) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL10245333 0.78 RIPK1 (0.54) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL13621571 0.78 TAAR1 (0.57) ADRA2BADRA1AHRH1OPRK1SLC6A3
SCHEMBL1541692 0.78 TAAR1 (0.57) ADRA2BADRA1AHRH1OPRK1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007002585-A1 COPOLYMERS OF C10+ ALPHA OLEFINS WITH OTHER ALPHA OLEFINS AND METHOD FOR COPOLYMERIZATION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (US) 2007-01-04 WO claimed
WO-2007002585-A1 COPOLYMERS OF C10+ ALPHA OLEFINS WITH OTHER ALPHA OLEFINS AND METHOD FOR COPOLYMERIZATION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (US) 2007-01-04 WO disclosed
EP-0952993-B1 POLYMERISATION PROCESS BP CHEM INT LTD (GB) 2004-10-06 EP disclosed
EP-1399491-A1 SUPPORTED DUAL TRANSITION METAL CATALYST SYSTEMS W.R. Grace & Co.-Conn. (US) 2004-03-24 EP disclosed
EP-1392741-A1 PROCESS FOR PREPARING SUPPORTED TRANSITION METAL CATALYST SYSTEMS AND CATALYST SYSTEMS PREPARED THEREBY W. R. Grace & Co.-Conn (US) 2004-03-03 EP disclosed
WO-2002088200-A1 SUPPORTED DUAL TRANSITION METAL CATALYST SYSTEMS W.R. GRACE & CO.-CONN. (US) 2002-11-07 WO disclosed
WO-2002088201-A1 PROCESS FOR PREPARING SUPPORTED TRANSITION METAL CATALYST SYSTEMS AND CATALYST SYSTEMS PREPARED THEREBY W. R. GRACE & CO.-CONN. (US) 2002-11-07 WO disclosed
US-6437060-B1 Process for the polymerization of olefins in the gas phase BP CHEMICALS LIMITED (GB) 2002-08-20 US disclosed
US-6437062-B1 Gas phase olefin polymerization process BP CHEMICALS LIMITED (GB) 2002-08-20 US disclosed
EP-0816394-B1 Process for polymerising ethylene in the gas phase BP CHEMICALS SNC (FR) 2002-01-30 EP disclosed
EP-0952993-A1 POLYMERISATION PROCESS BP Chemicals Limited (GB) 1999-11-03 EP disclosed
WO-1999000431-A1 PROCESS FOR THE POLYMERISATION OF OLEFINS IN THE GAS PHASE BP CHEMICALS LIMITED (GB) 1999-01-07 WO disclosed
WO-1998030605-A1 POLYMERISATION PROCESS BP CHEMICALS LIMITED (GB) 1998-07-16 WO disclosed
EP-0853091-A1 Polymerisation process BP CHEMICALS S.N.C. (FR) 1998-07-15 EP disclosed
EP-0816394-A1 Process from polymerising ethylene in the gas phase BP CHEMICALS S.N.C. (FR) 1998-01-07 EP disclosed