Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482339 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EKDM2BPLA2G1BATG4B | |
| SCHEMBL5475839 | 0.94 | HSD11B1 (0.55) | KDM4EKMT2APOLBMAPK1RAB9A | |
| SCHEMBL5475835 | 0.94 | HSD11B1 (0.55) | KDM4EKMT2APOLBMAPK1RAB9A | |
| SCHEMBL6210071 | 0.87 | HSD11B1 (0.64) | KDM4EKMT2APOLBHSD11B1LMNA | |
| SCHEMBL5478237 | 0.81 | PLA2G1B (0.75) | ALDH1A1KDM4EPLA2G1BATG4BMEN1 | |
| SCHEMBL5478240 | 0.81 | PLA2G1B (0.75) | ALDH1A1KDM4EPLA2G1BATG4BMEN1 | |
| SCHEMBL5480054 | 0.81 | KDM2B (0.58) | ALDH1A1KDM4EKDM2BHTTMEN1 | |
| SCHEMBL5480051 | 0.81 | KDM2B (0.58) | ALDH1A1KDM4EKDM2BHTTMEN1 | |
| SCHEMBL21928849 | 0.81 | HSD11B1 (0.71) | ALDH1A1MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL5474315 | 0.80 | HSD11B1 (0.68) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112000-A1 | Chemical compounds | ASTRAZENECA R&D ALDERLEY (GB) | 2007-05-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112000-A1 | Chemical compounds | HSD11B1, CYP11B1, HSD11B2 | ALDH1A1 68/4885KDM4E 1816/4885KDM2B 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.