Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614541 | 0.73 | — | — | |
| SCHEMBL22653561 | 0.69 | TDP1 (0.45) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11232970 | 0.67 | TDP1 (0.43) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5490340 | 0.67 | TDP1 (0.34) | TDP1 | |
| SCHEMBL9168764 | 0.65 | CYP3A4 (0.41) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL3095858 | 0.65 | CYP3A4 (0.41) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11155603 | 0.65 | CYP3A4 (0.41) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11690314 | 0.65 | CYP3A4 (0.41) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL1046753 | 0.65 | CYP3A4 (0.48) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL13236291 | 0.65 | CYP3A4 (0.41) | CYP3A4TSHRTDP1GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |