Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487709 | 0.81 | — | — | |
| SCHEMBL4810530 | 0.75 | PTPN1 (0.50) | TDP1PTPN1APEX1 | |
| SCHEMBL11398912 | 0.73 | TDP1 (0.39) | TDP1PTPN1APEX1 | |
| SCHEMBL2783155 | 0.72 | TDP1 (0.42) | TDP1PTPN1APEX1 | |
| SCHEMBL7025227 | 0.70 | TDP1 (0.40) | TDP1PTPN1APEX1 | |
| SCHEMBL10592008 | 0.69 | GABRA1 (0.44) | TDP1PTPN1APEX1 | |
| SCHEMBL3683193 | 0.67 | TDP1 (0.37) | TDP1PTPN1APEX1 | |
| SCHEMBL5482481 | 0.67 | CYP3A4 (0.36) | TDP1 | |
| SCHEMBL4812195 | 0.67 | CA1 (0.55) | TDP1PTPN1APEX1 | |
| SCHEMBL5490805 | 0.67 | PYCR1 (0.40) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |