Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 9/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463737 | 0.94 | PRMT5 (0.47) | CXCR3PRMT5TLR8NOD1NPC1 | |
| SCHEMBL5090938 | 0.90 | CXCR3 (0.47) | CXCR3PRMT5TLR8NOD1CXCR4 | |
| SCHEMBL5468452 | 0.87 | TLR8 (0.45) | CXCR3TLR8NPC1LMNATP53 | |
| SCHEMBL5473914 | 0.87 | PRMT5 (0.49) | CXCR3PRMT5TLR8NOD1CXCR4 | |
| SCHEMBL14470744 | 0.85 | CXCR3 (0.41) | CXCR3TLR8NPC1LMNATP53 | |
| SCHEMBL14373235 | 0.81 | PRMT5 (0.43) | CXCR3PRMT5TLR8NOD1TP53 | |
| SCHEMBL5453372 | 0.81 | TLR8 (0.41) | CXCR3TLR8NOD1NPC1LMNA | |
| SCHEMBL5462014 | 0.77 | DRD3 (0.49) | PRMT5TLR8TP53HTR1ADRD2 | |
| SCHEMBL5468418 | 0.76 | POLB (0.55) | CXCR3TLR8NOD1NPC1RAB9A | |
| SCHEMBL5472851 | 0.75 | PRMT5 (0.48) | PRMT5TLR8NOD1TP53CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | CXCR3 4743/4885PRMT5 2145/4885TLR8 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.