Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487980 | 0.78 | CYP3A4 (0.43) | HPGDALDH1A1KDM4EGAAMAPT | |
| SCHEMBL11495289 | 0.77 | HPGD (0.38) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL17704659 | 0.76 | ESR1 (0.48) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL10257025 | 0.74 | HPGD (0.43) | HPGDALDH1A1NPC1MAPTPDE2A | |
| SCHEMBL1774615 | 0.74 | HPGD (0.39) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL29783216 | 0.74 | HPGD (0.39) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL14483928 | 0.72 | HPGD (0.38) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL1363463 | 0.72 | HRH3 (0.39) | HPGDALDH1A1GAAMAPT | |
| SCHEMBL13463637 | 0.72 | HPGD (0.38) | HPGDALDH1A1NPC1NR2F2NOD2 | |
| SCHEMBL3398586 | 0.72 | HRH3 (0.39) | HPGDALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |