Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107538 | 0.78 | CYP3A4 (0.54) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL5482809 | 0.78 | HPGD (0.35) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL1755262 | 0.76 | MAPT (0.49) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL4026046 | 0.76 | CYP3A4 (0.48) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL30031076 | 0.76 | CYP3A4 (0.48) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL5488095 | 0.76 | — | — | |
| SCHEMBL92958 | 0.74 | S1PR1 (0.51) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL3763570 | 0.74 | CYP3A4 (0.46) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL11086985 | 0.74 | IDO1 (0.64) | CYP3A4ALDH1A1NPSR1MAPTKDM1A | |
| SCHEMBL109221 | 0.74 | CYP3A4 (0.52) | CYP3A4ALDH1A1NPSR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |