Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273049 | 0.95 | GAA (0.66) | GAAKMT2AHSD17B10F10PLG | |
| SCHEMBL31331780 | 0.84 | GAA (0.76) | GAAKMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL1928381 | 0.84 | GAA (0.76) | GAAKMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL18082335 | 0.82 | NPC1 (0.71) | GAAKMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL3023796 | 0.80 | GAA (0.73) | GAAKMT2AHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL14507774 | 0.80 | PLAU (0.54) | F10PLGPROCNPC1RAB9A | |
| SCHEMBL16105693 | 0.79 | KMT2A (0.67) | GAAKMT2AHSD17B10F10F3 | |
| SCHEMBL13702344 | 0.79 | AOC3 (0.54) | F10PLGPROCSMN1; SMN2HPGD | |
| SCHEMBL3634634 | 0.78 | MLYCD (0.58) | GAAKMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL3454176 | 0.77 | KMT2A (0.59) | GAAKMT2AHSD17B10F10F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129354-A1 | Biphenyl carboxylic amide p38 kinase inhibitors | GLAXOSMITHKLINE LLC | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129354-A1 | Biphenyl carboxylic amide p38 kinase inhibitors | MAPK1, MAPKAPK2, MAPK7 | GAA 2260/4885KMT2A 1855/4885HSD17B10 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.