SCHEMBL5483

SCHEMBL5483

CCOC(=O)C1CCC(=O)CC1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
PDK1 Q15118 1/20 0.46
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL4705578 0.96 ALDH1A1 (0.49) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
SCHEMBL17803290 0.93 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
SCHEMBL14115856 0.89 ALDH1A1 (0.47) ALDH1A1MAPTSMN1; SMN2ALOX15TSHR
SCHEMBL18501426 0.89 PDK1 (0.50) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
SCHEMBL337445 0.89 PDK1 (0.50) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
SCHEMBL14328268 0.89 PDK1 (0.50) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
Toluene SCHEMBL27495613 0.87 MEN1 (0.52) ALDH1A1MAPTSMN1; SMN2TSHRMEN1
SCHEMBL26620877 0.85 SOAT1 (0.47) ALDH1A1MAPTSMN1; SMN2PDK1ALOX15
SCHEMBL16214727 0.85 ALDH1A1 (0.58) ALDH1A1MAPTSMN1; SMN2TSHRHTT
SCHEMBL18845124 0.85 PPM1B (0.46) ALDH1A1MAPTSMN1; SMN2PDK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2863 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082192-B Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2024-09-13 CN claimed
CN-116120213-B Synthesis method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2024-09-13 CN claimed
CN-118026995-A Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone 国科大杭州高等研究院 2024-05-14 CN claimed
CN-117865889-A Synthesis method of benzisoquinoline compound 山东省药学科学院 2024-04-12 CN claimed
CN-116120213-A Synthesis method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-16 CN claimed
CN-116082192-A Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-09 CN claimed
CN-115850156-A Method for purifying difluoride compound 上海泰坦科技股份有限公司 2023-03-28 CN claimed
CN-113402428-B Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof 重庆医药高等专科学校 2023-03-03 CN claimed
CN-113789527-B Electrochemical synthesis method of aromatic amine 四川大学 2023-02-28 CN claimed
CN-114426497-A Preparation method of trans-4-aminocyclohexanecarboxylic acid hydrochloride 泰州精英化成医药科技有限公司 2022-05-03 CN claimed
CN-113789527-A Electrochemical synthesis method of aromatic amine 四川大学 2021-12-14 CN claimed
CN-113402428-A Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof 重庆医药高等专科学校 2021-09-17 CN claimed
CN-109678788-B 1, 2-diaryl indole, derivative and synthetic method thereof 湘潭大学 2021-05-04 CN claimed
CN-109678788-A A kind of 1,2- diaryl indoles, derivative and its synthetic method 湘潭大学 2019-04-26 CN claimed
CN-106563764-B A kind of 3D printing precoated sand material and preparation, forming method 共享智能装备有限公司 2019-04-23 CN claimed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
CN-122007826-A K-type thermocouple wire with high-temperature-resistant and oxidation-resistant coating and preparation method thereof 苏州航制领航测控技术有限公司 2026-05-12 CN disclosed
US-4001270-A ANTIINFLAMMATORY, ANTIBACTERIAL STERLING DRUG INC. (US) 1977-01-04 US disclosed
US-3948939-A 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids STERLING DRUG INC. (US) 1976-04-06 US disclosed
US-3931288-A ANTIINFLAMMATORY, ANTIRHEUMATIC HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed