Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033528 | 0.96 | LMNA (0.66) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL16439876 | 0.87 | LMNA (0.80) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL18427884 | 0.85 | ABCC4 (0.76) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL26084 | 0.85 | LMNA (1.00) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL11266426 | 0.84 | ALDH1A1 (0.54) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL8844919 | 0.83 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL28284677 | 0.83 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL28284672 | 0.83 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL384892 | 0.83 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL28284752 | 0.83 | LMNA (0.95) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |