Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848455 | 0.87 | CA2 (0.38) | TAAR1HTR2ACYP2A6IDO1 | |
| SCHEMBL5483581 | 0.86 | TAAR1 (0.46) | TAAR1HTR2ACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL5490192 | 0.85 | TAAR1 (0.45) | TAAR1HTR2ACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1579879 | 0.81 | TRPA1 (0.40) | TAAR1HTR2A | |
| SCHEMBL5490774 | 0.78 | TAAR1 (0.52) | TAAR1CYP2A6IDO1CNR1 | |
| SCHEMBL926567 | 0.78 | CA2 (0.37) | TAAR1 | |
| SCHEMBL840528 | 0.76 | CYP1A2 (0.50) | TAAR1CYP11B1CYP11B2CYP19A1CYP2A6 | |
| SCHEMBL27812323 | 0.76 | ESR1 (0.59) | TAAR1 | |
| SCHEMBL20004512 | 0.76 | TAAR1 (0.50) | TAAR1HTR2ACYP2A6IDO1HMOX1 | |
| SCHEMBL626076 | 0.76 | TAAR1 (0.68) | TAAR1HTR2ACYP2A6IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |