Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL548401 | 0.94 | MAPK14 (0.44) | MAPK14GALR1CD274HPGDKDM4E | |
| Morpholine SCHEMBL5963675 | 0.93 | MAPK14 (0.43) | MAPK14GALR1CD274HPGDKDM4E | |
| Dimethylamine SCHEMBL7797613 | 0.87 | KMT2A (0.47) | MAPK14GALR1KDM4EKMT2ADRD2 | |
| Dimethylamine SCHEMBL549202 | 0.84 | KMT2A (0.51) | MAPK14GALR1HPGDKDM4EKMT2A | |
| Dimethylamine SCHEMBL5963670 | 0.83 | KMT2A (0.50) | MAPK14GALR1HPGDKDM4EKMT2A | |
| Dimethylamine SCHEMBL549140 | 0.82 | HDAC4 (0.48) | MAPK14HPGDKDM4EKMT2ARIPK1 | |
| Dimethylamine SCHEMBL5963350 | 0.80 | HDAC4 (0.47) | MAPK14HPGDKDM4EKMT2ARIPK1 | |
| Trimethylammonium SCHEMBL5963612 | 0.77 | KMT2A (0.49) | CYP2D6MAPK14GALR1KDM4EKMT2A | |
| Morpholine SCHEMBL28644462 | 0.76 | LMNA (0.52) | OPRD1KCNH2CD274HPGDKDM4E | |
| Morpholine SCHEMBL5306223 | 0.76 | MAPK14 (0.43) | OPRD1CYP2D6OPRK1KCNH2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041584-A2 | IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |