Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659518 | 0.89 | NPC1 (0.59) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL22640297 | 0.89 | NPC1 (0.59) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL16583908 | 0.85 | NPC1 (0.63) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL20194464 | 0.85 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL12124399 | 0.84 | HPGD (0.71) | NAMPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL19480100 | 0.83 | KDM4E (0.58) | NAMPTNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL841649 | 0.82 | MAPK1 (0.56) | HPGDSNPC1RAB9AHDAC6KDM4E | |
| SCHEMBL15088518 | 0.82 | NAMPT (0.54) | NAMPTNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL5497348 | 0.82 | RAB9A (0.56) | NAMPTNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8996793 | 0.81 | NPC1 (0.51) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |