SCHEMBL5483740

SCHEMBL5483740

C=C[SiH](CCCCCCCCCCCCCCCCCC)CN(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.38
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769542 0.79 TSHR (0.42) DNM1TSHRTHRBALDH1A1
SCHEMBL5484215 0.77 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL5486020 0.77 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL8769516 0.76 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL5968696 0.73 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL25382520 0.72 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL25380882 0.69 TSHR (0.33) TSHRALDH1A1
SCHEMBL4526824 0.69 TSHR (0.46) DNM1TSHRTHRBALDH1A1
SCHEMBL6896851 0.69 TSHR (0.46) DNM1TSHRTHRBALDH1A1
SCHEMBL27285153 0.69 TSHR (0.46) DNM1TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1596193-B1 Novel stationary phases for use in high-performance liquid chromatography AGILENT TECHNOLOGIES INC (US) 2007-06-20 EP disclosed
US-20060076296-A1 Novel stationary phases for use in high-performance liquid chromatography AGILENT TECHNOLOGIES, INC. 2006-04-13 US disclosed
EP-1596193-A1 Novel stationary phases for use in high-performance liquid chromatography Agilent Technologies, Inc. (US) 2005-11-16 EP disclosed